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LC-0882 treatment resulted in inhibitory effects on cell invasion comparable to PAK4 knockdown. SGC7901 cells were incubated with indicated concentrations of LC-0882 for 24h. A: The invasive ability of SGC7901 treated with LC-0882 and PAK4 knockdowns were evaluated using a Boyden chamber matrigel invasion assay. B: The number of cells invading is shown as bar diagram ± SEM (left), **P<0.01. Western blot analysis was used to detect cellular protein levels of PAK4 (right).
