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IFN-induced stimulation of DKK1 is STAT3-dependent. A549 (A) and Calu-3 (B) cells were untreated or treated with FLUD, S3I, or αDKK1 alone or combined with IFNα, IFNγ or IFNλ1, respectively for 48 hours. DKK1 levels were evaluated by ELISA. Data represent a minimum of three independent experiments. Asterisks denote P<0.05 in comparison to untreated samples.
