CTC monitoring in a patient with HER2- positive breast cancer. CTC positivity: CTC+, AC: doxorubicin + cyclophosphamide, DH: docetaxel + herceptin, EA: axilla exenteration, dg: diagnosis, ER: oestrogen receptor, PR: progesteron receptor, HER2: human epidermal growth factor receptor, G: grade, CNS: central nervous system, markers of stem cells: CD44/CD24, markers of epithelial cells: KRT18/19 (keratins), EpCAM (Epithelial Cell Adhesion Molecule), MUC1 (mucin), markers of chemoresistance: see Table 2.