Table 2.
Enrichment analysis in miRNA clusters and families of the differential expressing miRNAs by Fisher’s exact test
| Items | Group | Nseta | Fold change | P value | Hitb |
|---|---|---|---|---|---|
| chr13_91351314_91351391 | Cluster | 6 | 23.79 | 1.18E-08 | mir-17; mir-20a; mir-19b-1; mir-92a-1 |
| chr3_160404745_160404825 | Cluster | 2 | 35.69 | 5.62E-06 | mir-15b; mir-16-2 |
| chrX_134169378_134169452 | Cluster | 6 | 17.85 | 9.22E-06 | mir-92a-2; mir-19b-2; mir-106a |
| mir-17 | Family | 8 | 17.85 | 2.59E-07 | mir-17; mir-20a; mir-93; mir-106a |
| mir-15 | Family | 5 | 21.42 | 2.28E-06 | mir-16-1; mir-15b; mir-16-2 |
Data was presented by Items, Group, Nset, Fold Change, P-value and hit. The enrichment analysis in miRNA clusters and families of the differential expressing miRNA was determined by Fisher’s exact test. P value <0.05 was considered significant.
a
Nset, the size of given miRNA cluster or family;
b
hit, differential expressing miRNAs in given cluster or family.