Table 6.

The correlation analysis between the expression level of miRNAs and characteristic of knee OA patients (n=100)

Parameters		miR-19b-3p	miR-92a-3p	miR-122-5p	miR-486-5p	miR-663a	miR-320b	miR-877-5p	miR-1180-3p
Age	r	0.128	0.254*	-0.086	0.423**	0.186	0.036	-0.038	0.040
	P_value	0.204	0.011	0.397	<0.001	0.304	0.721	0.706	0.692
Gender	r	0.186	0.086	-0.056	0.034	0.040	-0.154	0.075	-0.004
	P_value	0.063	0.396	0.581	0.740	0.693	0.127	0.456	0.970
Disease duration	r	0.354**	0.150	-0.045	0.222*	0.154	0.069	0.051	0.085
	P_value	<0.001	0.137	0.654	0.026	0.127	0.495	0.615	0.403
VAS pain rest	r	0.142	0.201	0.085	0.285**	0.103	0.224*	-0.093	0.110
	P_value	0.159	0.076	0.403	0.004	0.309	0.025	0.357	0.274
VAS pain walking	r	0.258**	0.195	-0.236*	0.336**	0.352**	0.078	0.026	0.044
	P_value	0.010	0.115	0.018	0.001	<0.001	0.438	0.800	0.666
WOMAC pain	r	0.302**	0.184	0.103	0.301**	0.135	0.146	0.005	0.067
	P_value	0.002	0.159	0.306	0.002	0.182	0.147	0.964	0.505
WOMAC stiffness	r	0.239*	-0.032	0.080	0.116	0.185	0.079	0.261**	0.115
	P_value	0.017	0.754	0.427	0.250	0.066	0.434	0.009	0.256
WOMAC function	r	0.122	0.202	0.137	0.310**	0.037	-0.064	-0.095	-0.076
	P_value	0.226	0.104	0.174	0.002	0.717	0.525	0.349	0.454
WOMAC total	r	0.191	0.198	0.141	0.352**	0.088	0.008	-0.022	-0.030
	P_value	0.057	0.184	0.162	<0.001	0.383	0.938	0.829	0.771

Data was presented as r and P value. Correlation was determined by Spearman test.

^* P value <0.05 was considered significant;

^** P value <0.01 was considered extremely significant.

OA, osteoarthritis; VAS, visual analogue scale; WOMAC, Western Ontarioand McMaster Universities Osteoarthritis Index.