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. 2017 Jun 15;9(6):2920–2932.

Figure 2.

Figure 2

Levels of WISP-1 and fibrotic markers in the obstructive kidney disease model were assessed using real-time PCR and western blot analyses. (A) Levels of collagen I, (B) fibronectin, (C) α-SMA and (D) WISP-1 mRNAs are significantly increased in UUO mice after 7 days compared to the sham mice according to the real-time PCR analysis. (E) Levels of collagen I, (F) fibronectin, (G) α-SMA and (H) WISP-1 proteins are significantly increased in the UUO mice after 7 days compared with the sham mice, as shown by western blot analyses. (I) Western blots for collagen I, fibronectin, α-SMA and WISP-1. α-SMA, α-smooth muscle actin; Col I, collagen I; FN, fibronectin; UUO, unilateral ureteral obstruction. **P<0.01, ***P<0.001 compared with the sham mice.