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. 2017 Jun 15;9(6):2945–2955.

Figure 2.

Figure 2

Expression of Piezo1 was up-regulated during heart failing process. A: mRNA levels of Piezo1 relative to GAPDH mRNA in right ventricle (RV), left ventricular infarction remote zone (RZ) and left ventricular infarction border zone (BZ) of hearts from Sham group, MI-4W group and MI-8W group (n=6 hearts per group). B: Protein levels of Piezo1 in RV, RZ and BZ of hearts from Sham group, MI-4W group and MI-8W group (n=6 hearts per group). C and D: Representative Piezo1 immunohistochemical staining sections and semiquantitative Piezo1 density of RV, RZ and BZ of hearts from Sham group, MI-4W group and MI-8W group (n=6 hearts per group). Data are presented as mean ± SEM. *P<0.05 vs Sham; #P<0.05 vs MI-4W. Oneway ANOVA analysis with Bonferroni test was performed among all groups.