. 2005 Feb 8;102(7):2620–2625. doi: 10.1073/pnas.0409583102

Table 1. Inhibitory binding constants, K_i (nM), for CRF ligands binding to sCRFR2α proteins.

Protein	CRF	rUcn 1	mUcn 2	mUcn 3	Astressin
Mam sCRFR2α	23 (14-39)	6.6 (3.5-12)	113 (68-190)	>200	6.7 (3.6-12)
Bact sCRFR2α	14.8 (9.2-24)	5.8 (2.5-13.3)	116 (85-158)	>200	10 (7.9-12.5)

Binding of CRF family members to sCRFR2α proteins purified from either COS M6 cell media [mammalian (mam) sCRFR2α] or E. coli [bacterial (bact) sCRFR2α]. See Materials and Methods for details. rUcn 1, rat Ucn 1; mUcn 2/3, mouse Ucn 2/3.

Table 1. Inhibitory binding constants, Ki (nM), for CRF ligands binding to sCRFR2α proteins.

Table 1. Inhibitory binding constants, K_i (nM), for CRF ligands binding to sCRFR2α proteins.