Fig. 5.

Highly virulent PA14 cells suppress AMP expression. (A) Fly survival after infection with PA14 and PA14-isogenic mutant D12. (B) Relative expression of 14 AMP genes in flies infected with PA14 vs. avirulent PA14-isogenic mutant D12 cells. Cecropin C′ refers to the splice variant of the gene. Color representations are the same as in Fig. 4. (C) Overexpression of the AMP genes AttA, CecA, Def, and Drc, but not Dipt or Drom, renders flies significantly less susceptible to PA14 infection (P < 0.0001; Table 4).