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. 2017 Jun 23;8:15674. doi: 10.1038/ncomms15674

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Copyright © 2017, The Author(s)

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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ZIKV replication detected in serum in the first 10 days p.i. and on days 15 and 30 p.i. Genome copies per ml in blood serum samples from individual macaques are shown logarithmically. Orange and black lines represent mean values for the DENV-immune and naïve macaques, respectively. The limit of detection, 500 genome copies per ml, of our assay is indicated in black dotted line.