Table 1.
Occurrence of proteins important for the InsP3 signaling pathway in some model organisms. The corresponding genes were searched for in the databases of Plasmodium, Toxoplasma, Homo sapiens, Trypanosoma and Paramecium (PlasmoDB, ToxoDB, PDB/NCBI, TriTrypDB and ParameciumDB, respectively). Phospholipase C of Paramecium tetraurelia is described in Klöppel et al., 2009 [27]. (1) Putative protein; (2) -like proteins; (3) encoded by pseudogene; (4) Leondaritis et al. (2013) [28], described 62 highly homologous phosphoinositide kinases genes; *genes that could not be found in databases.
|
Phosphatidyl
Inositol 4-kinase |
Phosphatidyl
Inositol 4-phosphate 5-kinase |
Phospholipase C |
Inositol
Polyphosphate 5-phosphatase |
Inositol 1,4,5-Trisphosphate
3-kinase |
Inositol Triphosphate Receptor | |
|---|---|---|---|---|---|---|
| Plasmodium falciparum 3D7 | PF3D7_0509800; PF3D7_0419900(1) | PF3D7_0110600; PF3D7_1129600(1) | PF3D7_1013500 | PF3D7_1354200(1) | * | * |
| Toxoplasma gondii ME49 | TGME49_328200 | TGME49_245730 | TGME49_248830 | * | * | * |
| Homo sapiens | AAA56839.1; BAA21661.1 | CAD99242.1 | AAA60112.1; BAA07688.1 | CAA74743.1; CAA67071.1 | AAH26331.1; CAC40650.1 | NP_002214.2 |
| Leishmania major Friedlin | LmjF.34.3590(1); LmjF.29.1450(1) | LmjF.36.0370(2); LmjF.34.3090(2); LmjF.35.0560(1,2) | LmjF.30.2950(2); LmjF.22.1680(1) | * | * | LmjF.16.0280(1) |
| Trypanossoma brucei gambiense | Tbg972.4.970(1) | Tbg972.10.4830(1) | Tbg972.11.6720(1) | * | * | Tbg972.8.2330(1) |
| Trypanossoma cruzi CL Brener | TcCLB.505987.70(1) | TcCLB.510289.30(1); TcCLB.511001.70(1) | TcCLB.508039.90(3) | * | * | BAM68694.1 |
| Paramecium tetraurelia | XP_001346932.1 | XP_001347030.1; XP_001347013.1 |
XP_001432600.1; XP_001426835.1 |
* | (4) | PTMB.445c |