Table 2.
Differentially expressed genes following α2B-adrenoceptor activation compared with vehicle-treated control according to IPA
| Gene symbol | Gene name | Fold change | P-value |
|---|---|---|---|
| Up-regulated genes | |||
| Lypd8 | LY6/PLAUR domain containing 8 | 2.01 | 4.2·10−6 |
| Glrx | glutaredoxin | 1.60 | 1.0·10−3 |
| LOC500300 | similar to hypothetical protein MGC6835 (Depp) | 1.58 | 4.0·10−3 |
| Procr | protein C receptor | 1.56 | 5.7·10−3 |
| Egr1 | early growth response 1 | 1.54 | 5.0·10−3 |
| Rpl37 | ribosomal protein L37 | 1.51 | 1.0·10−3 |
| Kif20a | kinesin family member 20a | 1.47 | 1.3·10−2 |
| Oasl | 2′-5′-oligoadenylate synthetase-like | 1.46 | 5.0·10−3 |
| Fam25a | family with sequence similarity 25, member A | 1.45 | 4.0·10−3 |
| Ppial4g | peptidylprolyl isomerase A like 4G | 1.45 | 2.3·10−2 |
| Down-regulated genes | |||
| Cx3cl1 | chemokine (C-X3-C motif) ligand 1 | −1.86 | 1.7·10−5 |
| Ccl2 | chemokine (C-C motif) ligand 2 | −1.74 | 4.4·10−4 |
| Ahnak | AHNAK nucleoprotein | −1.47 | 2.3·10−2 |
| Npm3 | nucleophosmin/nucleoplasmin 3 | −1.45 | 3.0·10−2 |
| Nid1 | nidogen 1 | −1.44 | 8.7·10−3 |
| Tnnt2 | troponin T2, cardiac type | −1.42 | 6.0·10−3 |
| Zfp36l2 | zinc finger protein 36, C3H type-like 2 | −1.40 | 4.4·10−2 |
| Ccl7 | chemokine (C-C motif) ligand 7 | −1.40 | 2.0·10−2 |
| Cav1 | caveolin 1 | −1.39 | 8.2·10−3 |
| Rhoa | ras homolog family member A | −1.38 | 2.4·10−2 |