Table 1.

Major clades in the D14/KAI2 family

	Clade	Taxon	Sequences	Major sub-clades
	KAI2	Klebsormidiales	2
	KAI2	Charales	1
	KAI2	Coleochaetales	3
	KAI2	Zygnematales	4
	NK2	Zygnematales	5
Eu-KAI2	KAI2A	Liverworts	9
	KAI2C/D	Mosses	19	KAI2C, KAI2D
	KAI2	Hornworts	5
	KAI2	Lycophytes	15
	KAI2	Monilophytes	27	KAI2G, KAI2H
	KAI2	Gymnosperms	18	KAI2I, KAI2J
	KAI2	Angiosperms	34
DDK	KAI2B	Liverworts	6
	KAI2E/F	Mosses	11	KAI2E, KAI2F
	DDK	Lycophytes	7
	DDK	Monilophytes	15	DDKA, DDKB
	DLK4	Gymnosperms	18	DLK4A, DLK4B
	D14	Gymnosperms	10
	D14	Angiosperms	37
	DLK23	Gymnosperms	23
	DLK23	Angiosperms	70	DLK2, DLK3

Table showing major clades in the D14/KAI2 family, as defined at the level of major taxonomic groups. Almost all sequences in the family unambiguously group into one of these clades. Within some clades there are major sub-clades where the lineage has been duplicated; these are listed at the right. Our analysis suggests that land plant D14/KAI2 proteins group into two super-clades, eu-KAI2 and DDK, as indicated on the left of the table