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. 2017 Jul;362(1):131–145. doi: 10.1124/jpet.117.240721

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Fig. 5. — Inhibition of visual chromophore regeneration in C57BL/6J mouse eyes by MB compounds. MB drugs were administrated to 1- to 2-month-old mice by oral gavage 24 or 4 hours (marked by asterisks) prior to light exposure for 10 minutes. Mice were then allowed to recover in darkness for 6 hours. The ocular 11-cis-retinal levels were measured by HPLC. Values are expressed as percentages of the control group (displayed as means ± S.D.; n = 3 for each group except the MB-008 group in which n = 9). DMSO, dimethylsulfoxide.