Table 2.

Treatment regimens for P. jirovecii colonization in COPD

First choice	Alternatives	Adjunctive corticosteroids
TMP-SMX (15–20 mg/kg TMP and 75–100 mg/ kg i.v. per day, divided q6h or q8h)	Clindamycin-primaquine, pentamidine (3–4 mg/kg i.v. per day)	Prednisone (40 mg p.o. b.i.d. 5 days, then 40 mg p.o. q.d. 5 days, then 20 mg p.o. q.d. for 11 days), methylprednisolone i.v. at 75% of prednisone dose, start at time of antibiotic initiation or at least within 72 h