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. 2017 May 23;6:741. [Version 1] doi: 10.12688/f1000research.10862.1

Table 1. Description of infections where protective or pathologic roles of IL-17 have been demonstrated.

Protective roles of IL-17 Pathologic role of IL-17
Extracellular bacteria Klebsiella pneumoniae 48, Citrobacter rodentium 49,
Staphylococcus aureus 50, and Bordetella pertussis 51
Bordetella pertussis 56, 69,
Porphyromonas gingivalis 66,
and Haemophilus influenza 70
Intracellular bacteria Listeria monocytogenes 71, Mycoplasma pulmonis 72,
Legionella pneumophila 73, 74, Salmonella typhimurium 75,
Chlamydia muridarum 76, Francisella tularensis 77, and
Mycobacterium tuberculosis 78
Mycobacterium tuberculosis 9698
Parasites Trypanosoma cruzi 104, Toxoplasma gondii 105,
Leishmania braziliensis 106, and Echinococcus
granulosus 107
Leishmania major 112, 113,
Leishmania guyanensis 114,
Eimeria tenella 115, and
Toxoplasma gondii 116
Fungus Candida albicans 117, Cryptococcus neoformans 118,
Pneumocystis carinii 119, and Aspergillus fumigatus 120
Candida albicans 130133 and
Aspergillus fumigatus 133
Virus H5N1 134136 and HIV 154, 155 H1N1 137139, respiratory
syncytial virus 144146, herpes
simplex virus 147, 148, Epstein-Barr
virus 149, 150, vaccinia virus 142, 143,
Dengue virus 153, hepatitis B and
C virus 140, 141, and HIV 159

HIV, human immunodeficiency virus; IL-17, interleukin-17.