Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Blockade of nuclear factor (NF)-κB activation by the proteasome inhibition. Inhibition of proteasome prevents the degradation of the natural inhibitor of NF-κB (i.e., IκB) along with nuclear translocation of p50/p65 and transcription of pro-inflammatory cytokines. Adapted from Verbrugge, [69]. TNF-α: tumor necrosis factor-α.
