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. 2017 May 18;10(2):47. doi: 10.3390/ph10020047

Scheme 1.

Scheme 1

Synthetic pathway of Compounds 16. Reagents and conditions: (i) DMAP, CH2Cl2, rt, 10 min; DCC, 0 °C, 30 min; rt, 10 h; (ii) HCl, CH3COOH. All esters were prepared as hydrochlorides.