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. 2017 Jun 20;10(2):56. doi: 10.3390/ph10020056

Table 4.

Anticipated radiation doses due to the use of 90Y-DOTATOC in humans and derived from PET studies with 86Y-DOTATOC in baboons and humans.

Organ Dose per Organ (mGy/MBq)
Baboon Study Rösch et al., [47] Baboon Study Rösch et al., with Amino Acid Cocktail Co-infusion [47] Human Study Förster et al., [72] Human Study Helisch et al., [73]
Intestine wall - - 0.05 ± 0.002 -
Kidneys 2.81 2.11 2.73 ± 1.41 1.71 ± 0.89
Liver 0.32 0.34 0.660 ± 0.002 0.72 ± 0.04
Other tissue - - 0.05 ± 0.002 -
Red marrow 0.07 0.03 0.05 ± 0.002 0.60 ± 0.02
Spleen - - 2.32 ± 1.97 2.19 ± 1.11
Urinary bladder wall 0.64 0.65 1.03 ± 0.23 -
Effective dose (mSv/MBq) 0.25 0.23 0.22 ± 0.07 0.17 ± 0.10