Figure 3. Subgroup analysis of the effect of SGLT2 inhibition on eGFR.

Pre-specified subgroup analyses were performed to address sources of heterogeneity. Weighted mean differences for eGFR are represented by small squares. The horizontal lines show 95% confidence intervals. The P values for subgroup differences are listed. Negative values indicate that the eGFR decrease was larger in the SGLT2 inhibition group compared with the control group.