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Effect of anticoagulants on thrombin generation in normal pooled plasma. Thin black line: no anticoagulant added; line of Xs: 200 nM otamixaban; closed dots: 400 nM melagatran; thin gray line: 0.08 U/mL unfractionated heparin; bold black line: 20 μg/mL dermatan sulfate; open dots: 0.9 μg/mL pentasaccharide.
