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Pooled data of stress (A) and [Ca2+]i transients (B) at varied [Ca2+]o (1-5 mM) from WT and gravin-t/t muscles. Both stress and [Ca2+]i transient increased as [Ca2+]o was raised. Stress was similar in both groups of muscles but [Ca2+]i transients remained significantly lower in gravin-t/t muscles (P<0.001; repeated MANOVA, n=8 in each group).
