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. Author manuscript; available in PMC: 2018 Jul 15.
Published in final edited form as: Eur J Pharmacol. 2017 Apr 17;807:117–126. doi: 10.1016/j.ejphar.2017.04.020

Fig. 3.

Fig. 3

Dynamics of stress and [Ca2+]i transient of trabecular muscles from WT and gravin-t/t mice. The time to peak stress (A) and [Ca2+]i (B) was prolonged in gravin-t/t muscles (as determined by MANOVA) whereas the time to 50% relaxation of stress (C) and [Ca2+]i (D) was not different between WT and gravin-t/t muscles. However, the initial relaxation time (time to 75% of peak) in twitch (E) was significantly slowed in gravin-t/t muscles (P<0.01 repeated MANOVA) whereas the initial relaxation time (time to 75% of peak) in [Ca2+]i (F) was not different between WT and gravin-t/t muscle. (n=8 in each group)