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. Author manuscript; available in PMC: 2018 Jul 10.
Published in final edited form as: Stat Med. 2017 Mar 26;36(15):2452–2465. doi: 10.1002/sim.7284

Table 5.

Analysis of ATLAS First 90 Days Data using the win ratio approach

W11+ W21 W12 W22
a: Death on Riva first 202,868 (14.8%)# 209,585.8 (15.1%) 202,868 (13.8%) 209,585.8 (14.0%)
b: Death on Placebo first 292,132 (21.4%) 304,607.4 (22.0%) 292,132 (19.8%) 304,607.4 (20.4%)
c: MI or Stroke on Riva first 392,876 (28.7%) 392,876 (28.3%) 440,620.4 (29.9%) 440,620.4 (29.5%)
d: MI or Stroke on Placebo first 480,285 (35.1%) 480,285 (34.6%) 536,990.6 (36.5%) 536,990.6 (36.0%)
Total: a + b + c + d 1,368,161 1,387,354 1,472,611 1,491,804
Win ratio: (b + d)/(a + c) 1.30 1.30 1.29 1.29
Reciprocal of Win ratio 0.77 0.77 0.78 0.78
 95% CI (0.63, 0.94) (0.63, 0.93) (0.64, 0.95) (0.63, 0.94)
p-value* 0.025 0.022 0.029 0.026
+

Wij is the weighted win loss statistics using weight (i) for the terminal event and weight (j) for the non-terminal event listed in Section 4.1;

#

the percentages in the parentheses are the contribution indexes as, for example, a/(a + b + c + d) × 100%;

*

p-values are from the tests based on the weighted win difference.