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Gradual changes in body composition and gut microbiota in mice fed sucralose. Changes in body weight (A), organ weight (B), and abundance of specific bacterial phylum and genus (C) after 8 weeks of sucralose feeding. Data represent mean ± S.E. (n = 8). * Concentration-dependent effects were observed by regression analysis, p < 0.05. LS: low sucralose (1.5 mg/kg BW/day), HS: high sucralose (15 mg/kg BW/day).
