Table 3.
Comparison between physiological, hemodynamic, and cognitive variables in patients with PMCI vs TCI at baseline and 1-month follow-up
| Mean (SD) | PMCI (N = 46) | TCI (N = 98) | p |
|---|---|---|---|
| Baseline | |||
| SBP baseline | 149.56 (22.56) | 150.94 (21.52) | 0.724 |
| DBP baseline | 80.4 (10.25) | 80.58 (10.14) | 0.919 |
| PSV baseline | 79.88 (18.86) | 78.75 (18.07) | 0.73 |
| EDV baseline | 30.82 (10.04) | 30.16 (9.63) | 0.705 |
| MFV baseline | 49.14 (12.57) | 48.95 (12.72) | 0.933 |
| PI baseline | 1.01 (0.23) | 1.01 (0.22) | 0.959 |
| CVRi baseline | 2.26 (0.72) | 2.29 (0.74) | 0.822 |
| MoCA baseline | 23.11 (2.77) | 21.87 (3.17) | 0.025 |
| 1-month follow-up | |||
| SBP FU | 134.14 (16.82) | 136.82 (18.22) | 0.401 |
| DBP FU | 72.9 (8.38) | 73.56 (9.11) | 0.677 |
| % SBP Diff | −9.05 (12.98) | −8.28 (13.71) | 0.749 |
| % DBP Diff | −8.46 (11.44) | −7.69 (13.49) | 0.737 |
| PSV FU | 81.80 (18.36) | 81.86 (16.32) | 0.98 |
| EDV FU | 33.73 (12.07) | 32.58 (9.68) | 0.547 |
| MFV FU | 51.01 (13.99) | 51.19 (12.37) | 0.939 |
| PI FU | 0.99 (0.24) | 0.98 (0.22) | 0.951 |
| CVRi FU | 1.97 (0.59) | 1.94 (0.52) | 0.73 |
| % PSV Diff | 6.41 (22.23) | 7.60 (20.36) | 0.756 |
| %EDV Diff | 11.79 (26.6) | 12.21 (28.84) | 0.934 |
| %MFV Diff | 6.67 (19.24) | 5.65 (22.63) | 0.78 |
| % PI Diff | −1.66 (16.50) | −2.18 (12.92) | 0.839 |
| % CVRi Diff | −10.25 (20.86) | −12.23 (18.36) | 0.567 |
| MoCA FU | 22.93 (3.36) | 25.8 (2.9) | <0.001 |
| MoCA Diff | −0.17 (1.61) | 3.93 (1.77) | <0.001 |
| MMSE FU | 25.24 (2.8) | 26.49 (2.62) | 0.012 |
PMCI: persistent mild cognitive impairment; TCI: transient cognitive impairment; FU: follow-up; SBP: systolic blood pressure (mmHg); DBP: diastolic blood pressure (mmHg); PSV: peak systolic velocity (cm/s); EDV: end-diastolic velocity (cm/s); MFV: mean flow velocity (cm/s); PI: pulsatility index; CVRi: cerebrovascular resistance index; MoCA: Montreal Cognitive Assessment; % Diff: percent change between baseline and follow-up; MoCA Diff: MoCA score change between baseline and follow-up; MMSE: Mini Mental State Evaluation.