Table 2.

Likely driver mutations caused by somatic L1 retrotransposon insertions in known proto-oncogenes and TSGs.

Gene	Location of Insertion	Tumor Type	Reference
APC	16th exon (coding)	Colorectal	Miki et al. 1992 [52]
APC	16th exon (coding)	Colorectal	Scott et al. 2016 [80]
PTEN	6th exon (coding)	Uterine	Helman et al. 2014 [74]
ST18	Intron (repressor)	Liver	Shukla et al. 2013 [72]