Table 4: Characteristics of Fluids Used for Shock Resuscitation.
Ringerlactate Hartmann® | Ringerfundin B. Braun® | Physiogel® | Albumin CSL 5 %® | |
Type of fluid | Crystalloid | Crystalloid | Colloid | Colloid |
- | - | Gelatine 4% (Mw 30,000 Da) | Human protein 5% (96% albumin; Mw 66,000 Da) | |
Natrium (mmol/l) | 131 | 140 | 154 | 140+4+4 |
Kalium (mmol/l) | 5.4 | 4 | 0 | 0 |
Magnesium (mmol/l) | 0 | 1 | 0 | 0 |
Calicium (mmol/l) | 1.8 | 2.5 | 0 | 0 |
Chloride (mmol/l) | 112 | 127 | 120 | 140 |
Lactate (mmol/l) | 28 | 0 | 0 | 0 |
Acetate (mmol/l) | 0 | 24 | 0 | 0 |
Malate (mmol/l) | 0 | 5 | 0 | 0 |
Tryptophanat (mmol/l) | 0 | 0 | 0 | 4 |
Caprylat (mmol/l) | 0 | 0 | 0 | 4 |
Osmolarity (mosmol/l) | 278 hypoton | 304 isoton | 274 hypoton | 265 hypoton |
pH | 5.0–7.0 | 4.6-5.4 | 7.1–7.7 | ? |
Adverse effects, risks | Fluid overload; elevated lactate levels | Fluid overload; | Fluid overload; anaphylactic reaction; urticaria; renal failure; coagulopathy | Fluid overload; anaphylactic reaction; viral infection; |
Contraindications a | Hyperkalaemia | pH > 7.50 | Anuria, oliguria; dialysis; pulmonary oedema; hyperchloremia, hyernatraemia | - |
Costs per 500ml a | 5 SFr | 3.70 SFr | 20 SFr | 120 SFr |
Da Dalton; Mw molecular weight. a According to the Swiss pharmaceutical compendium. b HES mean molecular weight 130,000 Dalton, substitution grade 0.4. HES is cleaved by serum amylases and then excreted by the kidneys. c Acetate is metabolised to bicarbonate causing metabolic alkalosis. 1 SFR corresponds to 0.96 EUR or 1.05 USD.