Figure 9.

Model for miR858-MYB83 interaction. Our results indicate that miR858 and MYB83 expression are connected through a feedback circuit in which miR858 regulates the expression of MYB83 and responds to its expression levels. This regulatory mechanism ensures proper expression levels of more than a thousand MYB83-regulated genes in the H. schachtii-induced syncytium. This fine-tuning mechanism appears to include MYB12, which was oppositely regulated by miR858 and MYB83, providing additional layer of tight control over gene expression.