Table 4. Patients reaching a low risk of disease progression (≤4 sites with PD≥5 mm) at 12 months.

Timepoints	Group A ITT: n = 28 PP: n = 26	Group B ITT: n = 25 PP: n = 24	Group C ITT: n = 27 PP: n = 25	Groups A-B (Fisher-Test)	Groups A-C (Fisher Test)	Groups B-C (Fisher Test)
ITT analysis (n = 80)	6/21.4%	18/72.0%	13/48.1%	<0.001s	0.049s	0.097
PP analysis (n = 75)	5/19.2%	17/70.8%	11/44.0	<0.001s	0.070	0.080

ITT: Intention to treat analyses, PP: per protocol analyses, PD: pocked depth, m: months