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. 2017 Jun 29;12(6):e0179745. doi: 10.1371/journal.pone.0179745

Table 7. Clinical, dermoscopic, confocal microscopy and histopathological features of positive and negative BRAF V600E melanomas.

BRAF V600E Clinic Dermoscopy Confocal microscopy Histopathology
POSITIVE Age < 50 (p = 0,022); Globular pattern with irregular globules; Blotches Hyporeflective cells in epidermis (p = 0,21); Epidermal nests (p = 0,019); Junctional nests (p = 0,035); Radial growth (p = 0,003); Vertical growth (p = 0,003)
NEGATIVE Age > 50 (p = 0,022); Atypical network; Sparse irregular globules; Radial projections; Irregular hypopigmentation; Veil; Peppering Edged papillae (p = 0,038); Junctional thickening cell aggregates (p = 0,012); Meshwork (p = 0,019); In situ (p = 0,003)