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. 2017 Jun 29;12(6):e0179776. doi: 10.1371/journal.pone.0179776

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© 2017 Narayanaswamy et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — (A) B. multivorans EH4, (B) B. multivorans AU10398, (C) B. cenocepacia AU10321. The lowest FIC index values of the combinations were reported as median +/- standard deviation. The graphs on the right column shows isoboles of Bcc strains exhibiting synergistic effects with the triple combination antibiotic treatment of meropenem, tobramycin and PAAG. The graphs on the left column exhibits isoboles of Bcc strains with a triple combination antibiotic treatment of meropenem, tobramycin and ceftazidime. The FIC values were chosen from the lowest concentration of antibiotics where addition of PAAG that could potentiate the effect of the antibiotics. Dotted line refers to FIC 0.5.