Table 1.
Baseline characteristics in the MZR and control groups
| Characteristic | MZR group (n = 21) | Control group (n = 21) | P |
|---|---|---|---|
| Age (yr) | 41.6 ± 14.7 | 43.2 ± 19.4 | 0.90 |
| Gender, men/women | 13/8 | 13/8 | 1.00 |
| Systolic blood pressure (mmHg) | 133.8 ± 15.8 | 127.5 ± 26.7 | 0.08 |
| Diastolic blood pressure (mmHg) | 81.7 ± 13.9 | 76.6 ± 15.4 | 0.30 |
| Serum creatinine (mg/dL) | 1.2 ± 1.0 | 1.2 ± 1.1 | 1.00 |
| eGFR (mL/min/1.73 m2) | 67.5 ± 30.4 | 67.4 ± 33.6 | 0.90 |
| Urinary protein excretion (g/gCr) | 0.90 ± 0.82 | 1.11 ± 1.36 | 0.83 |
| Serum albumin (g/dL) | 4.1 ± 0.6 | 4.2 ± 0.3 | 1.00 |
| Uric acid (mg/dL) | 5.7 ± 1.8 | 6.5 ± 1.7 | 0.29 |
| Serum IgA (mg/dL) | 306.7 ± 116.2 | 387.5 ± 190.1 | 0.15 |
| Duration of illness (y) | 4.6 ± 4.2 | 4.7 ± 5.0 | 0.74 |
| Japanese histological grade | |||
| Grade I | 15 (71.4) | 14 (66.7) | 0.79 |
| Grade II | 4 (19.0) | 4 (19.1) | |
| Grade III | 2 (9.5) | 2 (9.5) | |
| Grade IV | 0 (0.0) | 1 (4.8) | |
| Oxford classification | |||
| M0 | 17 (81.0) | 14 (66.7) | 0.48 |
| M1 | 4 (19.0) | 7 (33.3) | |
| E0 | 20 (95.2) | 18 (85.7) | 0.61 |
| E1 | 1 (4.8) | 3 (14.3) | |
| S0 | 9 (42.9) | 12 (57.1) | 0.54 |
| S1 | 12 (57.1) | 9 (42.9) | |
| T0 | 14 (66.7) | 16 (76.2) | 0.73 |
| T1 | 5 (23.8) | 3 (14.3) | |
| T2 | 2 (9.5) | 2 (9.5) | |
| Antiplatelet agents | 15 (71.4) | 17 (80.1) | 0.47 |
| RASI | 16 (76.2) | 17 (80.1) | 0.71 |
| Tonsillectomy | 16 (76.2) | 15 (71.4) | 0.73 |
| Steroid pulse therapy | 16 (76.2) | 16 (76.2) | 1.00 |
Values are presented as mean ± standard deviation, number only, or number (%).
Japanese histological grades are classified based on the percentage of the glomeruli exhibiting cellular or fibrocellular crescents, global sclerosis, segmental sclerosis or fibrous crescents (grade 1: < 25%, grade 2: 25 49%, grade 3: 50 74%, grade 4: ≥ 75%).
eGFR, estimated glomerular ltration rate; IgA, immunoglobulin A; MZR, mizoribine; RASI, renin angiotensin system inhibitors.