Table 2. The effects of Met and IOs on the body weight (g) in diabetic mice were analyzed.

	Week 0 (g)	Week 1 (g)	Week 2 (g)	Week 3 (g)	Week 4 (g)
CTRL	20.0±0.3	22.0±0.3	22.7±0.3	24.6±0.2	24.9±0.3
Model	19.8±0.2	16.0±0.4###	14.9±0.4###	15.2±0.3###	15.1±0.3###
Met	20.0±0.3	15.9±0.2	16.2±0.4*	17.3±0.5*	17.1±0.5*
IO1	19.8±0.3	16.8±0.3	16.5±0.4*	16.7±0.4*	16.8±0.3*
IO2	19.6±0.1	15.0±0.6	15.0±0.5	15.5±0.6	15.1±0.6^
IO3	19.7±0.2	15.3±0.5	15.3±0.5	15.7±0.8	16.6±0.5*
IO4	19.5±0.1	15.9±0.4	16.6±0.6*	17.1±0.5*	16.9±0.5*
IO5	19.6±0.2	16.6±±0.4	17.6±0.2**	17.9±0.3**	17.6±0.30**

Data are expressed as mean ± S.E.M. (n = 10) and analyzed by using a one-way ANOVA.

^### P < 0.001 versus normal controls

^* P < 0.05 and

^** P < 0.01 versus model group

^ P < 0.05 versus Met-treated group.