Table 4. The effects of Met and IOs on the changes of plasma glucose and area under the curve of glucose in diabetic mice were analyzed.

	blood glucose levels (mmol/L)					Area under the curve (h·mmol/L)
	0h	0.5h	1h	2h	4h
CTRL	4.2±0.4	13.4±0.7	7.5±0.5	4.1±0.2	3.8±0.2	15.5±0.7
Model	14.4±0.8###	27.7±1.3###	21.3±1.2###	16.0±1.1###	11.6±1.0###	41.4±1.3###
Met	10.8±0.8**	23.5±0.6**	18.4±0.8	11.7±0.5**	8.4±0.6*	34.1±0.8**
IO1	10.1±0.6**	27.6±1.2^	20.8±0.7^	14.4±0.7^	9.5±0.6	38.7±0.6^
IO2	9.8±0.7**	24.7±0.8	18.8±0.8	13.1±1.0^	7.3±1.0*	35.4±1.1*
IO3	11.1±0.9*	24.6±0.7	20.1±0.8^	13.7±0.8^	8.6±1.2	37.1±0.6^
IO4	9.3±0.9**	24.5±1.1	19.1±0.9	14.8±0.8^	8.4±1.0*	36.0±1.0*
IO5	8.8±0.9**	23.4±1.2*	18.1±0.9	13.9±0.5^	8.4±0.7*	34.4±0.8**

Data are expressed as mean ± S.E.M. (n = 10) and analyzed by a one-way ANOVA.

^### P < 0.001 versus normal controls

^* P < 0.05 and

^** P < 0.01 versus model group

^ P < 0.05 versus Met-treated group.