Table 1.
Effect of HIFD on infiltrating inflammatory cells 2 days post–I/R injury
| Cell Type | Treatment | ||
|---|---|---|---|
| Sham | Vena Cava | HIFD | |
| CD4+ | 6272±3839 | 21,101±4198a | 9987±2964b |
| CD8+ | 5097±4506 | 15,444±2637a | 8474±1468b |
| B cells | 2351±1510 | 5743±1609 | 2868±880b |
| DC/Macs | 12,695±5433 | 34,684±7758 | 21,495±3880b |
| CD4+IL-4+ (Th1) | 161±58 | 280±52.8 | 200±50 |
| CD4+IFN-γ+ (Th2) | 277±82 | 1301±667 | 399±113 |
| % CD4+Foxp3+ | 0.7±0.01 | 0.405±0.04 | 0.72±0.08b |
| % CD8+Foxp3 | 0.35±0.1 | 0.15±0.02a | 0.29±0.06 |
The table shows different subtypes of infiltrating mononuclear cells in the kidney 48 hours postinjury in sham, I/R + vena cava, or I/R + HIFD. The data are shown as the number of cells/g of kidney. Data are expressed as mean±SEM.
a
P<0.05 sham versus I/R + vena cava.
b
P<0.05 in I/R + vena cava versus I/R + HIFD.