Table 1.
Patient characteristics
| Clinical Characteristic | Active Rejection Group | No Active Rejection Group | P Valuea |
|---|---|---|---|
| Number of patients | 27 | 75 | |
| Number of samples | 27 | 80 | |
| Race, n (%) | 0.23 | ||
| Black | 13 (48) | 23 (31) | |
| White | 13 (48) | 41 (55) | |
| Native Hawaiian or Other Pacific Islander | 1 (4) | 0 (0) | |
| Hispanic/Latino | 0 (0) | 4 (5) | |
| Asian | 0 (0) | 1 (1) | |
| Other | 0 (0) | 6 (8) | |
| Men, n (%) | 16 (59) | 45 (60) | >0.99 |
| Age at enrollment, y | 46±16 | 53±13 | 0.04 |
| Post-transplant, d | 968±1107 | 1189±1482 | 0.42 |
| CMV serologic status, n (%) | 0.15 | ||
| D−/R+ | 4 (15) | 13 (17) | |
| D+/R+ | 5 (19) | 24 (32) | |
| D−/R− | 3 (11) | 16 (21) | |
| D+/R− | 4 (15) | 9 (12) | |
| Unknown | 11 (41) | 13 (17) | |
| Donor type, n (%) | 0.03 | ||
| Deceased donor | 20 (74) | 42 (56) | |
| Living unrelated | 2 (7) | 24 (32) | |
| Living related | 5 (19) | 9 (12) | |
| Child | 2 (7) | 3 (4) | |
| Sibling | 2 (7) | 4 (5) | |
| Parent | 0 (0) | 1 (1) | |
| Half-sibling | 0 (0) | 0 (0) | |
| Other biologic blood relation | 1 (4) | 1 (1) | |
| Creatinine | 2.5±1.0 | 2.4±1.4 | 0.69 |
| eGFR | 32±12 | 36±21 | 0.21 |
| HLA class 1 no. of mismatches (A, B) | 2.7±1.4 | 2.6±1.4 | 0.59 |
| HLA class 2 no. of mismatches (DR) | 1.2±0.6 | 1.1±0.8 | 0.67 |
| Weight, kg | 85±19 | 84±21 | 0.73 |
| Height, cm | 170±10 | 171±8 | 0.58 |
Data ranges are presented as mean±standard deviation. CMV, cytomegalovirus.
a
The P values are the level of statistical significance in the differences of values found in the DART active rejection group and the no active rejection group. For continuous covariates, Wilcoxon rank sum test was used to generate the P values. For categoric covariates, Fisher exact test was used to generate the P values.