Fig 5. CHIKV mAb therapy reduced plasma cytokines and chemokine activation at 2 dpi.

Heat map comparing average fold-change in plasma cytokine profiles for NHP treated inoculated with CHIKV and treated with control antibody SVIR002 or CHIKV mAb SVIR001. Clustering was performed using the Broad Institute’s webtool Morpheus. A 29-plex-cytokine magnetic bead assay was performed on plasma from rhesus macaques isolated at day 0, 1, 2, 3, 5, and 7 post-infection.