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. Author manuscript; available in PMC: 2017 Aug 21.
Published in final edited form as: Phys Med Biol. 2016 Jul 27;61(16):6105–6120. doi: 10.1088/0031-9155/61/16/6105

Table 1.

Relevant Features. p <= 0.05 and Generalization Score > 0.75.

Categories Features Thresholds Percent of pneumonitis
(N=201)
Comorbidities 1.DLCO adj %* < 38.5 23.5% vs 1.6%
2. Referring Provider Pulmonology + Thoracic Surgery and Pulmonology 10.8% vs 2.4%
Dosimetric Indices 1. Chest Wall Dose to 30 cc >2498.8 cGy 8.9% vs 0.8%
2. Skin Dose to 10 cc >1387 cGy 11.8% vs 1.3%
3. Lung Dose 1 - 10% >701.2 cGy 7.8% vs 0%
4. Lung Mean Dose >264.6 cGy 7.6% vs 0%
5. Heart Dose to 15 cc >83.2 cGy 7.5 vs 0%
6. Heart Dmax >114.8 cGy 3.7% vs 0%
7. Trachea/Bronchus Dose to 4 cc >34.85 cGy 5.7% vs 0%
8. Rib Dmax >5423.85 cGy 7.1% vs 1.7%
9. Trachea/Bronchus Dose to 4 cc >25 cGy 6.6% vs 0%
10. Lung Dose 2–15% >316.7 6.6% vs 0%
Fractionation 1. Number of Fractions 3 or 5 vs. 4 6.9% vs 1.8%
2.Dose per Fraction 1000+2000 cGy 6.9% vs 1.8%
Risk Factors 1.Marial Status Married or Divorced 6.3% vs 0%
2. Race White 5.9% vs 0%
3. Weight >153 lbs 6.6% vs 0%
Staging 1. Tumor Size (cm) >3.45 25.0% vs 2.6%
2. PTV Volume (cc) >32.8 11.5% vs 0.7%
Tumor Location Tumor location.
R= right, L = left + Upper, Medium, Lower
LL+RLL+RUL 6.1% vs 0%
*

Feature with missing values. There is less than a 50% chance that the p values of the bolded features (p ≤ 0.011) happened randomly.