Fig. 4.

Pathway map of steroid degradation. The green arrow shows the degradation process of sterol side-chain, the blue arrow show the degradation of steroid nucleus. The dashed arrow indicate multiple enzymatic. AD 4-androstadiene-3,17-dione, 9-OHADD, 9α-hydroxy-1,4-androstadiene-3,17-dione, ChO cholesterol oxidase, 3β-HSD 3-beta-hydroxy-delta-5-steroid dehydrogenase, CYP125A cytochrome P450 125A1, FadD family putative fatty-acid-CoA ligase (fadD15,17,19), FadE family acyl-CoA dehydrogenase (fadE26,27,28,29,34), FadB family enoyl-CoA hydratase (ech19, hsd4B), FadA family acetoscetyl-CoA thiolase (fadA5, Ltp3), hsd4A Hydroxy-CoA dehydrogenase, KstD 3-Ketosteroid-1-dehydrogenase, KSH (KshA and KshB), 3-ketosteroid-9α-hydroxylase