Fig. 4. Tonic GABA current was increased by reactive astrocytes at DIV 7. (A~C) Representative traces of tonic currents from control (A), Ad-CMV-mCherry-infected (B), and putrescine-treated (C) conditions. (D) Magnitude of bicuculline (BIC, 50 µM)-sensitive tonic currents in control, putrescine-treated and viral infected conditions, as indicated. ^***p<0.001, one-way ANOVA, Dunnetts's test. (E, F) Representative traces of passive conductance from control (E) and Ad-CMV-mCherry-infected (F) conditions. (G) Current-voltage relationship (I~V) from -160 mV to +60 mV.