Activated leukocyte cell adhesion molecule (ALCAM) transcript numbers and grade tumor, node, metastasis (TNM) stage, nodal status, and Nottingham Prognostic Index (NPI). (a) The ALCAM transcript number and the grade of tumor. Grade 1 is well differentiated, Grade 2 is moderately differentiated, and Grade 3 is poorly differentiated (mean ± standard deviation). (b) The ALCAM transcript number and the TNM staging (mean ± standard deviation). Note that there were only four patients with TNM Stage 4 disease. (c) The ALCAM transcript number and regional nodal status (mean ± standard deviation). (d) The ALCAM transcript number and NPI. NPI-1 represents the good prognostic group with scores < 3.4, NPI-2 represents the moderate prognostic group with scores of 3.4–5.4, and NPI-3 represents the poor prognostic group with scores > 5.4 (mean ± standard deviation).