Table 1.

AP classification.

Classification	Severity	Local complications	Systemic complications			Reference
			TOF	POF	EPC
Atlanta 2012a	Mild	×	×	×	×	(10, 11)
	Moderate	√	√	×	√
	Severe	√	×	√	√/×
Determinant basedb	Mild	×	×	×	N/A
	Moderate	Sterile	√	×	N/A
	Severe	Infected	√	√	N/A
	Critical	Infected	×	√	N/A

AP, acute pancreatitis; EPC, exacerbation of preexisting comorbidity; N/A, not applicable; POF, persistent organ failure; TOF, transient organ failure; √, yes; ×, no.

^aIn Atlanta 2012, local complications are subcategorized (interstitial edematous, necrotizing pancreatitis, infected necrotizing pancreatitis, other local complications, etc.), whereas systemic complications are defined as TOF or POF or an EPC (organ failure persisting for >48 h; three organ systems = renal, respiratory, cardiovascular; Marshal score ≥2).

^bSepsis-related organ failure assessment scoring system is used to define organ failure, and for severe pancreatitis, either POF or infected necrosis is mandatory.