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. 2017 Jun 30;8:762. doi: 10.3389/fimmu.2017.00762

Table 4.

Characteristics of clinical trials on ω-3 FAs as the nutritional supplements in AP.

Reference Subjects/regions Dosage (g/kg BW/day) Method of assessment AD-EN or PN interval (h) Duration of EN or PN (days) Infectious complication (n/N) Mortality (n/N) DOS (days mean ± SD)




Cont. Interv. Cont. Interv. Cont. Interv. Cont. Interv.
Lasztity et al. (69) 28/Hungary 3.3 g/day APACHE
CT severity index
<24 17.57 ± 10.52 10.57 ± 6.70 1/14 2/14 19.28 ± 7.18 13.07 ± 6.70

Wang et al. (70) 40/China 0.2 APACHE <72 5 5 5/20 3/20 2/20 0/20 70.5 ± 9.1 65.2 ± 7.3

Wang et al. (71) 28/China 0.2 APACHE
CT severity index
<72 5 5 9/28 6/28 2/28 0/28

AD, the interval between admittance to ICU and start of enteral or parenteral nutrition; AP, acute pancreatitis; APACHE, acute physiology and chronic health evaluation; Cont., control; DOS, duration of hospital stay; EN, enteral nutrition; Interv., intervention; PN, parenteral nutrition; ω-3 FAs, omega-3 fatty acids.