Table 4.
Multivariate analysis of the relationships between body composition parameters and overall survival for patients with esophagogastric cancer
| Variables | No. of patients | No. of deaths n (%) | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|---|---|
| HR | (95% CI) | p value | HR | (95% CI) | p value | |||
| Age (years) | ||||||||
| ≤65 | 46 | 23 (33) | 1.148 | 0.832–1.584 | 0.402 | 1.578 | 1.03–2.417 | NS |
| 65–74 | 40 | 27 (40) | ||||||
| ≥75 | 22 | 12 (35) | ||||||
| Sex | ||||||||
| Female | 33 | 18 (35) | 1.026 | 0.593–1.777 | 0.926 | 1.145 | 0.605–2.167 | 0.667 |
| Male | 75 | 44 (37) | ||||||
| TNM stage | ||||||||
| 1 | 30 | 5 (14) | 2.390 | 1.681–3.398 | <0.001 | 2.782 | 1.766–4.382 | <0.001 |
| 2 | 43 | 30 (41) | ||||||
| 3 | 35 | 27 (44) | ||||||
| Neoadjuvant therapy | ||||||||
| Yes | 43 | 20 (32) | 1.579 | 0.926–2.691 | 0.093 | 2.111 | 1.015–4.388 | NS |
| No | 65 | 42 (39) | ||||||
| Adjuvant therapy | ||||||||
| Yes | 42 | 23 (35) | 0.719 | 0.429–1.206 | 0.719 | 0.403 | 0.22–0.737 | NS |
| No | 66 | 39 (37) | ||||||
| Lymphovascular invasion | ||||||||
| Yes | 51 | 34 (40) | 1.722 | 1.037–2.859 | 0.036 | 0.814 | 0.425–1.560 | NS |
| No | 57 | 28 (33) | ||||||
| Neutrophil count (×109/L) | ||||||||
| <7.5 | 87 | 48 (36) | 1.033 | 0.549–1.946 | 0.919 | 1.048 | 0.517–2.124 | NS |
| ≥7.5 | 19 | 12 (39) | ||||||
| Subcutaneous fat index (cm2/m2) | ||||||||
| High | 38 | 24 (39) | 0.912 | 0.678–1.228 | 0.545 | 0.934 | 0.627–1.39 | NS |
| Medium | 33 | 19 (37) | ||||||
| Low | 37 | 19 (34) | ||||||
| Visceral fat index (cm2/m2) | ||||||||
| High | 38 | 26 (41) | 0.786 | 0.571–1.083 | 0.141 | 0.738 | 0.473–1.152 | NS |
| Medium | 38 | 21 (36) | ||||||
| Low | 32 | 15 (32) | ||||||
| Skeletal muscle index (cm2/m2) | ||||||||
| Normal | 85 | 48 (36) | 1.165 | 0.642–2.114 | 0.616 | 0.761 | 0.351–1.649 | NS |
| Sarcopenia | 23 | 14 (38) | ||||||
HR hazard ratio, CI confidence interval, TNM tumor-node-metastasis