Figure 6. Reversal potential of the 5‐HT‐activated current in type II cells.

A, the current evoked by 5 μm 5‐HT (I_5‐HT) was inward at more negative holding potentials and outward at more positive potentials; note that I _5‐HT sometimes showed multiple peaks (e.g. at −80 and +40 mV), which may reflect different conductance states. The reversal potential of I _5‐HT for a group of five cells was approximately –11 mV (B), which is consistent with activation of non‐selective ion channels.