Figure 2.

The System taxonomy includes five subsets and is based on the position of three core functions: a national HTA performing agency, if present, in relation to the position of the regulatory authority (REG) and the decision-making coverage body (CB). The five-subset of the System taxonomy: S₁–the regulatory, HTA and coverage body functions are performed by separate agencies. S₂–the regulatory and HTA functions are performed by a single agency and the coverage body functions are independent. S₃–the HTA and coverage body functions are performed by a single agency with the regulatory function performed independently. S₄–the regulatory, HTA and coverage body functions are all performed within a single agency. S₅–no HTA is performed within the national regulatory to reimbursement system.