Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Apr 12;5(2):9. doi: 10.3390/vaccines5020009

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Application of alphaviral expression vectors. Plasmid DNA/RNA replicons and recombinant particles can be used for heterologous expression. In the case of DNA and RNA replicon delivery, appropriate transfection methods for host cells have to be established, whereas recombinant particles naturally provide a broad range of host cell susceptibility. All vectors will provide expression of heterologous proteins, but only full-length RNA and replication-proficient vectors will provide new virus progeny.