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. 2017 May 2;5(2):10. doi: 10.3390/vaccines5020010

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Assessment of kinetics of antibody production: the figure shows IgG total of all groups of mice bled weekly, from Day 7 (one week after the first vaccination) to Day 35 (one week after the second boost). The results were analysed using GraphPad Prism software applied to assess the means of five groups by one-way analysis of variance (one-way ANOVA). The values observed in the negative control group were subtracted from the titres of the other experimental groups. Note: *** = p value < 0.0001; ** = p value < 0.001; * = p value < 0.01.