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. 2017 Jun 6;17(6):1306. doi: 10.3390/s17061306

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Simultaneous monitoring of secretory activity and intracellular ATP levels during chondrogenesis. (A) Time course data taken with simultaneous monitoring of PxRe intensity (red line) and secreted Cypridina luciferase (CLuc) intensity (blue line) during perfusion with insulin-implemented medium. Reproduced with permission from [65]. (B) Effect of 2-deoxy glucose (2-DG) treatment on the oscillatory secretion of CLuc during perfusion with insulin-implemented medium. Reproduced with permission from [65]. (C) Simultaneous monitoring of PxRe intensity (red line) and secreted BMP2 levels (blue line) during perfusion with the chondrogenic medium. Reproduced with permission from [76]. (D) Simultaneous monitoring of PxRe intensity (red line) and secreted TGF-β1 levels (blue line) during perfusion with chondrogenic medium. Reproduced with permission from [67]. Reproduced with permission from [76].